THE REGENERATION OF AUTOGRAFTS OF THYROID TISSUE IN PARTIALLY AND COMPLETELY THYROIDECTOMIZED RATS

Abstract

Using mature [female] rats it was found that the transplanted thyroid gland (to the ovary) grows rapidly and shows microscopic evidence of increased cellular activity when a definite state of thyroid deficiency exists (after complete thyroidectomy). But when a portion of the thyroid is left in place, the transplanted portion grows slowly with no sign of cellular hyperactivity, and never attains appreciable size. The portion left in situ shows no increased growth or activity.