HEMODYNAMIC CHANGES IN SALT DEPLETION AND IN DEHYDRATION 12

Abstract

Salt depletion in untraumatized animals produces a form of peripheral vascular collapse closely resembling that seen in traumatic shock. Plasma vol., cardiac output, circulation rate, and blood pressure all decline sharply, and protein disappears from the plasma. Water depletion alone with a comparable decline in extracellular volume does not produce peripheral vascular collapse, although cardiac output, plasma vol., mean arterial pressure, and the circulation rate may decline. Usually little or no protein disappears from the plasma.