INTERSTITIAL DELETION OF SHORT ARM OF CHROMOSOME-11 LIMITED TO WILMS TUMOR-CELLS IN A PATIENT WITHOUT ANIRIDIA
- 1 January 1981
- journal article
- research article
- Vol. 41 (11), 4577-4578
Abstract
An interstitial deletion of the short arm of a chromosome 11 was found in Wilms'' tumor cells of a patient without aniridia. The chromosomes in her peripheral blood lymphocytes were normal. The karyotype of the tumor cells is similar to that reported for the somatic cells of patients with aniridia-Wilms'' tumor association. The same cytogenetic change as that seen in patients with this condition, namely, an interstitial deletion of 11p13, can occur in patients without aniridia as a mutation that is confined to tumor cells.This publication has 6 references indexed in Scilit:
- A deleted chromosome no. 13 in human retinoblastoma cells: relevance to tumorigenesisCancer Genetics and Cytogenetics, 1981
- Chromosomal Imbalance in the Aniridia-Wilms' Tumor Association: 11p Interstitial DeletionPediatrics, 1978
- Retinoblastoma and Subband Deletion of Chromosome 13Archives of Pediatrics & Adolescent Medicine, 1978
- Further evidence for a non‐random chromosomal abnormality in acute promyelocytic leukemiaInternational Journal of Cancer, 1977
- High Resolution of Human ChromosomesScience, 1976
- Association of Wilms's Tumor with Aniridia, Hemihypertrophy and Other Congenital MalformationsNew England Journal of Medicine, 1964