Studies on the total synthesis of CC-1065: preparation of a synthetic simplified 3-carbamoyl-1,2-dihydro-3H-pyrrolo[3,2-e]indole dimer/trimer/tetramer (CDPI dimer/trimer/tetramer) and development of methodology for PDE-I dimer methyl ester formation
- 1 April 1987
- journal article
- research article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 52 (8), 1521-1530
- https://doi.org/10.1021/jo00384a026
Abstract
No abstract availableThis publication has 15 references indexed in Scilit:
- Preliminary toxicity studies with the DNA-binding antibiotic, CC-1065.The Journal of Antibiotics, 1984
- Parameters of preparative centrifugal thin-layer chromatographyChromatographia, 1982
- CC-1065 (NSC-298223), A MOST POTENT ANTI-TUMOR AGENT - KINETICS OF INHIBITION OF GROWTH, DNA-SYNTHESIS, AND CELL-SURVIVAL1982
- MECHANISM OF INTERACTION OF CC-1065 (NSC-298223) WITH DNA1982
- The structure of CC-1065, a potent antitumor agent and its binding to DNAJournal of the American Chemical Society, 1981
- CC-1065(NSC 298223), a potent new antitumor agent. Improved production and isolation, characterization and antitumor activity.The Journal of Antibiotics, 1981
- Total Synthesis of PDE-IIAgricultural and Biological Chemistry, 1979
- Total Synthesis of PDE-IAgricultural and Biological Chemistry, 1979
- Isolation and Characterization of PDE-I and II, the Inhibitors of Cyclic Adenosine-3′,5′-monophosphate PhosphodiesteraseAgricultural and Biological Chemistry, 1978
- CC-1065 (NSC-298223), a new antitumor antibiotic. Production, in vitro biological activity, microbiological assays and taxonomy of the producing microorganism.The Journal of Antibiotics, 1978