Die Diffusionskapazität der Lunge bei Silikose
- 1 January 1966
- journal article
- research article
- Published by S. Karger AG in Respiration
- Vol. 23 (5), 283-293
- https://doi.org/10.1159/000192492
Abstract
As compared with healthy persons of the same ages an average reduction of the CO-diffusing capacity of 8. 1% at rest and 4.2% during effort of 80 watt was found by the steady state method (Filley et al. in 85 patients with non-obstructive silicosis. There was no relationship between the stage of silicosis as shown by X-ray and the extent of the diffusing capacity. At rest 15%, and during effort 3% respectively of those investigated showed a reduced diffusing capacity which was for the most part slight. No significant correlation was demonstrable either at rest or during effort between diffusing capacity and arterial PO2 [oxygen pressure]. Compared with the normal subjects the silicotics showed hyperventilation both at rest and during effort. This is considered to be the result of the increase in the size of the functional dead space and its causes and effects on Dco [co diffusing capacity] are discussed. A disorder of distribution is regarded as the essential cause of the limitation of diffusing capacity in silicotics.This publication has 10 references indexed in Scilit:
- ELECTRON MICROSCOPY OF HUMAN PULMONARY EMPHYSEMAPublished by Elsevier ,1965
- Comparative Pulmonary Function StudiesArchives of environmental health, 1964
- Pulmonary diffusing capacity of athletesJournal of Applied Physiology, 1963
- EFFECT OF BREATHING OXYGEN UPON CARDIAC OUTPUT, HEART RATE, VENTILATION, SYSTEM AND PULMONARY BLOOD PRESSURE IN PATIENTS WITH CHRONIC LUNG DISEASE1963
- PULMONARY DIFFUSING CAPACITY: A COMPARISON OF BREATH-HOLDING AND STEADY STATE METHODS USING CARBON MONOXIDEJCI Insight, 1961
- THE DIFFUSING CAPACITY OF THE PULMONARY MEMBRANE AND THE PULMONARY CAPILLARY BLOOD VOLUME IN CARDIOPULMONARY DISEASE1958
- On the Significance of CO Tension in Pulmonary Capillary Blood for Determination of Pulmonary Diffusing Capacity with the Steady State CO Method.1Acta Medica Scandinavica, 1957
- A Simple Electrometric Technique for the Determination of Carbon Dioxide Tension in Blood and Plasma, Total Content of Carbon Dioxide in Plasma, and Bicarbonate Content in “Separated” Plasma at a Fixed Carbon Dioxide Tension (40 mm Hg)Scandinavian Journal of Clinical and Laboratory Investigation, 1956
- CARBON MONOXIDE UPTAKE AND PULMONARY DIFFUSING CAPACITY IN NORMAL SUBJECTS AT REST AND DURING EXERCISE 1JCI Insight, 1954
- THE UPTAKE OF CARBON MONOXIDE IN HEALTH AND IN EMPHYSEMA1952