The Use of a Water-Soluble Carbodiimide as a Coupling Reagent in the Passive Hemagglutination Test
- 1 December 1966
- journal article
- research article
- Published by The American Association of Immunologists in The Journal of Immunology
- Vol. 97 (6), 791-796
- https://doi.org/10.4049/jimmunol.97.6.791
Abstract
Summary: A simplified method is described for coupling proteins to red cells using the water-soluble carbodiimide, 1 - ethyl - 3 - (3 - dimethylaminopropyl) carbodiimide hydrochloride. The procedure is simpler than BDB coupling and the sensitized cells are more stable than those in the BDB system. The data indicated a marked similarity in the specificity and sensitivity of ECDI-and BDB-hemagglutination.This publication has 8 references indexed in Scilit:
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