Mass spectra of prostaglandins: II. Trimethylsilyl and alkyloxime‐trimethylsilyl derivatives of prostaglandins B1 and B2

Abstract

The mass spectra of the trimethylsilyl ester trimethylsilyl ether derivatives of prostaglandins B₁ and B₂, and of theirO-ethyl andO-methyl oximes are reported and discussed. The high resolution spectra of these compounds are also considered. These spectra are compared with those of the correspondingd ₉-trimethylsilyl derivatives and of the selectively labeled trimethylsilyl esterd ₉-trimethylsilyl ethers. The base peaks of the spectra of the trimethylsilyl derivatives are formed by sequential loss of C₅H₁₁ (by cleavage of C-15/6) and of CO (from the ring). The spectra of the oxime-trimethylsilyl derivatives are dominated by ions resulting from loss of the alkoxy group of the oxime moiety.