Modulation of Candida albicans attachment to human epithelial cells by bacteria and carbohydrates
- 1 March 1983
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 39 (3), 1354-1360
- https://doi.org/10.1128/iai.39.3.1354-1360.1983
Abstract
The effects of carbohydrates (mannose and dextrose). Escherichia coli 07KL. and Klebsiella pneumoniae on Candida albicans attachment to epithelial cells was studied. Dextrose had no effect on yeast attachment to epithelial cells. Conversely, mannose significantly decreased both yeast and piliated bacterial attachment (E. coli 07KL, heavily piliated K. pneumoniae) whereas having no effect on nonpiliated K. pneumoniae attachment to epithelial cells. The number of yeasts attaching to epithelial cells was enhanced by preincubation of epithelial cells with piliated strains of bacteria, whereas preincubation with nonpiliated strains of bacteria had no effect on yeast attachment. Scanning electron microscopy showed that piliated bacteria and yeasts were juxtaposed on the epithelial cell surface. These data suggest that certain piliated strains of bacteria can enhance C. albicans attachment to epithelial cells and that type 1 pili of bacteria can be a factor in the enhanced attachment of C. albicans to epithelial cells.This publication has 34 references indexed in Scilit:
- ENVIRONMENTAL ALTERATION AND 2 DISTINCT MECHANISMS OF ESCHERICHIA-COLI ADHERENCE TO BLADDER EPITHELIAL-CELLS1981
- Evaluation and Treatment of Urinary CandidiasisSouthern Medical Journal, 1979
- The Fimbrial and Non-Fimbrial Haemagglutinins of Escherichia ColiJournal of Medical Microbiology, 1979
- SURFACE-LAYER OF CANDIDA-ALBICANS1978
- CYTOCHEMICAL-LOCALIZATION OF PHOSPHOLIPASE IN CANDIDA-ALBICANS INFECTING CHICK CHORIOALLANTOIC MEMBRANE1977
- The infection of rat tongue mucosa in vitro with five species of candidaJournal of Medical Microbiology, 1976
- HOST-PARASITE INTERACTION IN THE RAT RENAL PELVISThe Journal of Experimental Medicine, 1974
- The Occurrence of Yeast-Like Fungi in the Urine Under Normal Conditions and in Various Types of Urinary Tract PathologyScandinavian Journal of Urology and Nephrology, 1972
- VISUALIZATION OF NEW ULTRASTRUCTURAL COMPONENTS IN THE CELL WALL OF CANDIDA ALBICANS WITH FIXATIVES CONTAINING TAPOThe Journal of cell biology, 1972
- Fungus infections of the urinary tract.1958