Distribution of PNMT and Epinephrine in the medulla oblongata of normotensive and spontaneous hypertensive rats
- 1 December 1979
- journal article
- research article
- Published by Springer Nature in Journal of Neural Transmission
- Vol. 44 (4), 309-316
- https://doi.org/10.1007/bf01250326
Abstract
The distribution of the Epinephrine forming enzyme (PNMT) activity and Epinephrine (E) levels was investigated in the medulla oblongata of spontaneous hypertensive rats (SH-rats) and in two normotensive strains, namely Wistar Kyoto rats (WK-rats) and Wistar rats. The PNMT activity increases progressively from the caudal to rostral parts in the C1 and C2 regions of the medulla oblongata. The enzyme activity and the E levels are in all parts of the C1 and C2 regions higher in Wistar rats than in WK-rats. The PNMT activity in all parts of the C2 region (with the exception of the caudal region), and in the middle part of the C1 region is higher in SH-rats than in WK-rats. The E levels in the SH-rats are higher than in WK-rats in the mediocaudal parts of the C2 and C1 regions.This publication has 14 references indexed in Scilit:
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