A Genetic and Molecular Analysis of DNA Repair in Drosophila

Abstract

Overview Mutant isolation and characterization Mutant sources Mutagen-sensitive mutants (mus) Meiotic mutants (mei) Mutations producing gene and chromosome instability Genetic and cytological analyses Mutant influences on meiosis Mutant influences on mutation Identification of defects in DNA repair Photorepair Excision repair Postreplication repair Additional repair processes Molecular cloning of DNA repair genes Cloning strategy Mutation induction by transposon tagging Progress report Enzymology related to DNA repair