A Gene Controlling Condensation of Heterochromatin in Drosophila melanogaster
- 1 July 1983
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 221 (4605), 83-85
- https://doi.org/10.1126/science.6407113
Abstract
A temperature-sensitive lethal mutant of Drosophila melanogaster was used to identify an essential cell cycle function that is necessary for the mitotic condensation of heterochromatic but not of euchromatic portions of the genome. This mutant is an allele at a locus (mus-101) identified earlier by the use of mutagen-sensitive mutants. The data suggest that the mutagen-sensitive and repair-defective phenotypes of viable mus-101 mutants result from a disruption in chromosome organization.Keywords
This publication has 14 references indexed in Scilit:
- Abnormal recovery of DNA replication in ultraviolet-irradiated cell cultures of Drosophila melanogaster which are defective in DNA repairMolecular Genetics and Genomics, 1981
- Postreplication repair-defective mutants of Drosophila melanogaster fall into two classesMolecular Genetics and Genomics, 1981
- Genetic analysis of X-linked mutagen-sensitive mutants of Drosophila melanogasterMutation Research, 1981
- Sensitivity of drosphila mutants to chemical carcinogensMutation Research, 1979
- CELL CYCLE MUTANTSAnnual Review of Genetics, 1978
- THE UTILIZATION DURING MITOTIC CELL DIVISION OF LOCI CONTROLLING MEIOTIC RECOMBINATION AND DISJUNCTION IN DROSOPHILA MELANOGASTERGenetics, 1978
- ISOLATION AND CHARACTERIZATION OF X-LINKED MUTANTS OF DROSOPHILA MELANOGASTER WHICH ARE SENSITIVE TO MUTAGENSGenetics, 1976
- CHARACTERIZATION OF POSTREPLICATION REPAIR IN MUTAGEN-SENSITIVE STRAINS OF DROSOPHILA MELANOGASTERGenetics, 1976
- Evidence for heterogeneity in heterochromatin of Drosophila melanogasterNature, 1975
- ANALYSIS OF THE CHROMOSOME ABERRATIONS INDUCED BY X-RAYS IN SOMATIC CELLS OF DROSOPHILA MELANOGASTERGenetics, 1974