Mediterranean Diet, Alzheimer Disease, and Vascular Mediation

Abstract

Dietary pattern analysis has recently received growing attention in relation to many diseases (ie, cirrhosis or various cancers) because individuals do not consume foods or nutrients in isolation but rather as components of their daily diet. Defining diet by dietary patterns has the ability to capture its multidimensionality while reducing its apparent complexity because patterns can integrate complex or subtle interactive effects of many dietary constituents and bypass problems generated by multiple testing and the high correlations that may exist among these constituents.¹ Part of the explanation for some of the conflicting findings in the literature regarding dietary constituents and Alzheimer disease (AD) risk could be the result of individual food or nutrient approach. Nevertheless, there is paucity of data regarding the effect of composite dietary patterns on the risk for AD.