A man with presumptive Y/Y translocation, observed in a forensic psychiatric department
- 1 August 1976
- journal article
- research article
- Published by Wiley in Clinical Genetics
- Vol. 10 (2), 82-88
- https://doi.org/10.1111/j.1399-0004.1976.tb00017.x
Abstract
A man charged with a sexual offence had a complex karyotype anomaly, including a Y-chromosome of aberrant structure. Other features were very small stature, skeletal deformities and obscure neurological defects. There were no gross psychiatric symptoms, nor was there mental retardation. Q and G-banding and photometric scanning of the chromosomes of the propositus and his 3 healthy brothers indicated that the aberrant Y-chromosome probably arose from a reciprocal translocation, which may be written: t(Y:Y) (qter .fwdarw. p11: :q11 .fwdarw. qter). Fibroblast cultures differed from the lymphocytes; in the former the majority of the cells lacked the abnormal Y-chromosome, their karyotype being 45,XO.This publication has 11 references indexed in Scilit:
- Translocations causing non-fluorescent Y chromosomes in human XO/XY mosaicsHereditas, 2009
- A case of trisomy-G with a simultaneous balanced D-D translocationHereditas, 2009
- Isochromosome Y [46, X, i(Yq)] and female phenotypeClinical Genetics, 1973
- Human Dicentric Y Chromosomes: Case Report and Review of the LiteratureJournal of Medical Genetics, 1973
- Are variations in length of Y chromosome due to structural changes?Hereditas, 1971
- Satellites on the long Y chromosome arm: a familial Y/autosome translocation in manCytogenetic and Genome Research, 1969
- A Presumptive Y-Autosome Translocation in a Boy With Congenital MalformationsArchives of Pediatrics & Adolescent Medicine, 1968
- Presumptive Y/D translocation in mixed gonadal dysgenesis.Journal of Medical Genetics, 1967
- Hypogonadism Associated with Chromosomal Break in Autosome No. 2 and Translocation Presumably on the Y ChromosomeJournal of Clinical Endocrinology & Metabolism, 1965