Substances Capable of Decreasing the Acid Solubility of Tooth Enamel

Abstract

147 substances, comprising compounds of 57 elements, have been tested for possible effect on the acid solubility of powdered tooth enamel. The investigations were carried out independently in 2 laboratories by slightly different procedures. The substances were dissolved in water or acetic acid buffer and placed in contact with enamel powder for a few minutes. Acid solubility of enamel after this treatment was compared with the solubility before treatment. 27 compounds were more active in reducing acid solubility than 0.1% NaF, and 38 were less active but definitely effective. Compounds of cations of Groups III and IV of the periodic table were among the most active substances. Several other compounds of fluoride were more active than NaF in depressing enamel solubility.