CORTILACTIN, THE LACTATION FACTOR OF THE ADRENAL

Abstract

A lactation factor was prepared from the adrenal by iso-electric precipitation. The pigeon crop gland response was used for its assay. The best cortilactin preparation possessed about 1/10 of the potency of purified prolactin when tested by the crop gland method. The daily inj. of 1 mg. of the cortilactin prep. into an adrenalectomized rat maintained on cortin induced normal lactation. The pup survival was 100% and their avg. wt. was normal. Cortilactin plays no role in gluconeogenesis.