SODIUM CHLORIDE AND DIABETES INSIPIDUS

Abstract

In the permanent, but not the transient, phase of diabetes insipidus, the onset and continuance of the large fluid exchange are to a large extent dependent upon the ingestion of NaCl. If none is ingested, as in fasting or with diets low in NaCl, the diabetes insipidus is almost, but not entirely, prevented. The changes in water metabolism in diabetes insipidus are probably secondary to changes in NaCl metabolism.