Dose-rate and Survival Curves
- 1 August 1965
- journal article
- research article
- Published by Oxford University Press (OUP) in The British Journal of Radiology
- Vol. 38 (452), 607-612
- https://doi.org/10.1259/0007-1285-38-452-607
Abstract
A model is proposed for the effect of dose-rate on the survival curve leading to a set of differential equations, which are solved numerically. Parameters of the model have been fitted to published data on survival of HeLa S3 cells, and a satisfactory fit obtained. Resulting survival curves have a dose-rate dependent component together with an exponential component independent of dose-rate. Reasons are given for expecting the exponential component to be relatively independent of the oxygen effect.Keywords
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