The 26 S proteasome is activated at two points in the ascidian cell cycle
- 28 September 1992
- journal article
- Published by Wiley in FEBS Letters
- Vol. 310 (2), 119-122
- https://doi.org/10.1016/0014-5793(92)81310-i
Abstract
The proteasome undergoes cell cycle-dependent changes in its subcellular distribution during ascidian embryonic development [(1992) Dev. Biol. 151, 27–33]. In this study, we demonstrate that the 26 S proteasome is markedly activated in both prophase and metaphase of the mitotic cell cycle in the ascidian embryos in comparison with the case of the 20 S proteasome. These results suggest that the 26 S proteasome is activated and participates in proteolysis at the restricted stages of the cell cycle.Keywords
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