High protein diets and acid-base mechanism

Abstract

[long dash]On diets consisting largely of caseinogen and containing the usual proportion of yeast, subnormal rat growth is restored to normal by the inclusion of further amounts of yeast. The need for fixed base when high protein diets are given is met by 5% of McCollum''s salt mixture. No evidence of kidney damage was obtained in rats which were fed for 6 mos. on diets containing 70% caseinogen. Uncoagulated egg-white in the diet of rats is rapidly fatal. Subnormal growth occurred with diets containing 20% coagulated egg-white, as well as with 66% egg-white which produced acute fatal nephritis. Fecal N and urinary indican suggested excessive putrefaction on these diets.