Two different theta (θ) globin gene deletions observed among black newborn babies
- 1 February 1988
- journal article
- research article
- Published by Wiley in British Journal of Haematology
- Vol. 68 (2), 249-253
- https://doi.org/10.1111/j.1365-2141.1988.tb06197.x
Abstract
Two different .theta.1 globin gene deletions have been detected in the Black population of the southeastern U.S.A. Restriction mapping of the .alpha. globin gene cluster indicated that one deletion removes .apprx. 1.8 kb of DNA including most of the .theta.1 globin gene, while the second removes .apprx. 6 kb of DNA including the entire .theta.i globin gene. These defects do not cause haematological alterations in the newborn or in the adult (established for the smaller deletion only), nor were changes observed in polypeptide chain patterns at birth.This publication has 14 references indexed in Scilit:
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