Two different quadruplicated α globin gene arrangements
- 1 June 1987
- journal article
- Published by Wiley in British Journal of Haematology
- Vol. 66 (2), 245-250
- https://doi.org/10.1111/j.1365-2141.1987.tb01306.x
Abstract
The discovery of two different types of alpha globin gene quadruplication is reported. One with the alpha alpha alpha alpha (anti 3.7)/haplotype was present in four members of a Black family from Georgia, while a second with the alpha alpha alpha alpha (anti 4.2)/haplotype was observed in two members of an Indonesian family. Consistent clinical and haematological manifestations could be observed in these heterozygotes.Keywords
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