THE EFFECT OF TESTOSTERONE PROPIONATE ON THE URINARY EXCRETION OF ANDROGENS AND ESTROGENS IN EUNUCHOIDISM1,2,3

Abstract
In 4 eunuchoids, intramusc. inj. of 25 mg. testosterone propionate per day for 9-14 days caused rises in urinary androgens from basal levels of 2 to 16 I.U. per day to 44 to 115 I.U. per day, and of urinary estrogens from the equivalents of 0.3 to 5 [gamma] of estrone per day to 5-15 [gamma] of estrone per day. This is a restoration to normal in both groups of substances. In 3 patients in whom the cause of hypogonadism was unknown the extent of recovery of administered testosterone was 65, 49 and 49%. In a patient whose pituitary was damaged by a suprasellar cyst, recovery was 20%.