A SYNTHETIC ADJUVANT EFFECTIVE IN INDUCING ANTITUMOR IMMUNITY
- 1 July 1988
- journal article
- research article
- Published by Wiley in Japanese Journal of Cancer Research
- Vol. 79 (7), 817-820
- https://doi.org/10.1111/j.1349-7006.1988.tb00042.x
Abstract
Guinea pigs which were injected repeatedly with a mixture of a 3M KCl extract of line 10 tumor and 6-0-(2-tetradecyl-hexadeconoyl)-muramyl-dipeptide (B30-MDP) rejected a tumor graft of line 10. Such an adjuvant effect of B30-MDP was also demonstrated when X-ray-treated line 10 cells were mixed with B30-MDP dissolved in phosphate-buffered saline and inoculated into the animals.Keywords
This publication has 16 references indexed in Scilit:
- Synthesis of 6-O-Acyl Derivatives of Immunoadjuvant Active N-Acetylmuramyl-l-alanyl-d-isoglutamineBulletin of the Chemical Society of Japan, 1978
- IMMUNOTHERAPY OF ESTABLISHED MICROMETASTASES WITH BACILLUS-CALMETTE-GUERIN TUMOR-CELL VACCINE1978
- Synthesis of long chain fatty acid esters of N-acetylmuramyl-L-alanyl-D-isoglutamine in relation to antitumor activityTetrahedron Letters, 1978
- IMMUNOADJUVANT ACTIVITIES OF SYNTHETIC 6-O-ACYL-N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE WITH SPECIAL REFERENCE TO EFFECT OF ITS ADMINISTRATION WITH LIPOSOMES1977
- Synthesis of 6-o-mycoloyl-n-acetylmuramyl-l-alanyl- D-isoglutamine with immunoadjuvant activityTetrahedron Letters, 1976
- Protective Tumor Immunity Induced by Potassium Chloride Extracts of Guinea Pig HepatomasJNCI Journal of the National Cancer Institute, 1975
- Immunoadjuvant activities of synthetic N-acetyl-muramyl-peptides or -amino acids.1975
- Minimal structural requirements for adjuvant activity of bacterial peptidoglycan derivativesBiochemical and Biophysical Research Communications, 1974
- Antigenic Specificity of Hepatomas Induced in Strain-2 Guinea Pigs by DiethylnitrosamineJNCI Journal of the National Cancer Institute, 1969
- Antigenicity of a New Diethylnitrosamine-Induced Transplantable Guinea Pig Hepatoma: Pathology and Formation of Ascites VariantJNCI Journal of the National Cancer Institute, 1968