RESUMPTION OF FUNCTION OF AUTOPLASTIC ADRENOCORTICAL TRANSPLANTS TO THE DORSAL MUSCULATURE IN RATS

Abstract

Seven days after operation, adrenalectomized rats with autoplastic adrenocortical transplants to the dorsal musculature recover from doses of histamine which would kill adrenalectomized rats (10 or 15 mg./100 g. body wt.). Rats with transplants, 7 days after operation, survive a 4-hr. exposure to cold (2[degree]C) which would kill adrenalectomized rats, and by 10 days after operation they maintain normal colonic temps. Rats with transplants exhibit some resistance to water intoxication by 10 days after operation, and the maximum of which they are capable by about the 30th post-operative day, but they never recover a normal resistance to this stress.