Mendelian Randomization
- 21 November 2017
- journal article
- review article
- Published by American Medical Association (AMA) in JAMA
- Vol. 318 (19), 1925-1926
- https://doi.org/10.1001/jama.2017.17219
Abstract
This JAMA Guide to Statistics and Methods reviews the concepts underlying mendelian randomization and provides examples of its application to clinical trial desKeywords
This publication has 8 references indexed in Scilit:
- Genetic Association of Waist-to-Hip Ratio With Cardiometabolic Traits, Type 2 Diabetes, and Coronary Heart DiseaseJAMA, 2017
- Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median EstimatorGenetic Epidemiology, 2016
- Common variants associated with plasma triglycerides and risk for coronary artery diseaseNature Genetics, 2013
- Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation studyThe Lancet, 2012
- Major Lipids, Apolipoproteins, and Risk of Vascular DiseaseJAMA, 2009
- Genetically Elevated C-Reactive Protein and Ischemic Vascular DiseaseNew England Journal of Medicine, 2008
- Association of Loss-of-Function Mutations in the ABCA1 Gene With High-Density Lipoprotein Cholesterol Levels and Risk of Ischemic Heart DiseaseJAMA, 2008
- ‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*International Journal of Epidemiology, 2003