RAT EAR AS A SITE FOR ADRENAL CORTICAL GRAFTS AND SUBSEQUENT EAR-ADRENALECTOMY1
- 1 January 1942
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 30 (1), 150-157
- https://doi.org/10.1210/endo-30-1-150
Abstract
Comparison is made of body wt. changes and mortality of over 100 adrenalectomized rats following autotransplants to the pinnae; and removal of the grafts from rats that survived with wt. changes and mortality of control adrenalectomized rats. Transplants were successful in approx. 50% (no salt licks) and 34% (salt licks) of the [male][male]. 48% of these 2 groups died after graft removal as contrasted with 95-100% of the control series. They survived 37% longer than the controls. 7% (no salt licks) and 36% (salt licks) of the [female][female] possessed successful transplants and 40% of these died after graft removal and survival periods that exceeded the controls. The marked decrease in mortality after graft removal indicated that more rats possessed accessory cortical tissue than might be concluded from the high mortality % obtained with controls. Visibility and the certain removal of all of the graft quickly and with negligible trauma served as the basis for a suggested exptl. method that would largely eliminate factors of anesthetics, traumatic shock, post-operative healing, and the uncertain role of accessory cortical tissue from expts. on adrenalectomized rats.This publication has 2 references indexed in Scilit: