EFFECT OF PREVIOUS CASTRATION ON WEIGHT LOSS AND SURVIVAL OF ADRENALECTOMIZED RATS*

Abstract

Gonadectomy of 28 [female][female] 6-20 wks. prior to 2-stage adrenalectomy had no significant effect on the degree of wt. loss, % of mortality or length of survival. 6 to 7-wks. castrated [male][male] lost on the avg. of 3% more wt. and lived 3 days longer than normal [male][male]. Results on castrated [male][male] are almost identical with those of [female][female]. Removal of 2d adrenal while the animal was in estrus seemed to have no effect on the survival period.