Performance of British Landrace pigs selected for high and low incidence of halothane sensitivity

Abstract

Halothane positive and negative selection lines were established to estimate the effects of the halothane gene on performance in British Landrace pigs. Incidences of positive reaction diverged from 0·12 in the foundation generation to 0·93 in the positive and to 0·02 in the negative line in generation 4. Differences in litter productivity as a trait of the dam were estimated from a total of 399 positive × positive and negative × negative parity 1 and 2 matings in generations 1 to 4.Compared with negative contemporaries, positive females showed non-significant reductions in litter size at birth (−0·10, s.e. 0·26) and at 42 days (−0·28, s.e. 0·26), accompanied by significant reductions in average piglet weights at birth (−0·11, s.e. 0·02 kg) and 42 days (−0·4, s.e. 0·2 kg). There were no differences in conception rate or adult live weights. A subsample of 69 parity 2 and 3 sows slaughtered 30 days after mating showed no significant difference in ovulation rate or embryo survival, but for positive dams the length of embryos was significantly reduced (−3·1, s.e. 1·1 mm).The study suggests that the principal effect of the halothane gene was in reducing foetal growth rather than litter size. However, the phenotypic difference is expected to under-estimate the genetic difference between homozygotes, and it was not possible to distinguish the effects of dam and offspring genotypes. The present economic loss of roughly £4·70 per positive litter would be unlikely to justify elimination of the gene from a purebred maternal Landrace herd.