Heart Failure in Addison's Disease with Myocardial Changes of Potassium Deficiency
- 1 January 1944
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 4 (1), 30-34
- https://doi.org/10.1210/jcem-4-1-30
Abstract
Foci of necrosis of cardiac muscle were found in the myocardium of a patient with Addison''s disease. These foci closely resembled those produced in animals by excessive doses of desoxycorticosterone or by a diet deficient in K. The patient had a constant source of desoxycorticosterone from sub-cutaneously implanted pellets, but received practically no K in the diet. This is believed to be the 1st human example of anatomically demonstrable effect of excessive desoxycorticosterone and/or K deficiency.This publication has 6 references indexed in Scilit:
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- ADDISON'S DISEASE: EVALUATION OF SYNTHETIC DESOXYCORTICOSTERONE ACETATE THERAPY IN 158 PATIENTSAnnals of Internal Medicine, 1942
- The production of cardiac and renal lesions in rats by a diet extremely deficient in potassium1942
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