THE EFFECT OF GONADECTOMY ON BODY STRUCTURE AND BODY WEIGHT IN ALBINO RATS

Abstract
Gonadectomy produced no predictable or significant variations in weight of albino rats, when observed over a period of 52 weeks. The gonadectomized [female][female] were larger and heavier than "controls." This was due to increased growth, as shown by chem. analyses of carcass and x-ray studies of skeleton. The animals were kept in the usual rat cages and were not subjected to activity expts. In N balance expts. the operated and control animals behaved alike. Gonadectomy does not produce obesity; it stimulates growth in the [female] presumably through its effects on the growth hormone of the hypophysis.