Studies in detoxication

Abstract

It has been shown that, in the rabbit, acetanilide is oxidized almost entirely to p-acetamidophenol, which is excreted in the urine as p-acetamidophenylglucuronide and p-acetamidophenylsulfuric acid, these occurring in the ratio 6:1. Less than 5% of the acetanilide fed is deacetylated and only traces of aniline and unchanged acetanilide were isolated.