Contribution of Candida albicans ALS1 to the Pathogenesis of Experimental Oropharyngeal Candidiasis
Open Access
- 1 September 2002
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 70 (9), 5256-5258
- https://doi.org/10.1128/iai.70.9.5256-5258.2002
Abstract
We investigated the contribution of Candida albicans ALS1, which encodes a candidal adhesin, to the pathogenesis of experimental murine oropharyngeal candidiasis. Our results indicate that the ALS1 gene product is important for the adherence of the organism to the oral mucosa during the early stage of the infection.Keywords
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