Orotic Acid and Related Compounds in the Nutrition of Lactobacillus bulgaricus 09
- 1 October 1950
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 75 (1), 293-297
- https://doi.org/10.3181/00379727-75-18175
Abstract
The orotic acid requirement of Lactobacillus bulgaricus 09 can be met by ureidosuccinic acid (10-20% as active as orotic acid) or by 5-(carboxy-methylidine)-hydantoin (30-40% as active as orotic acid) but not by any one of a large group of related or unrelated compounds studied. The data are taken as micro-biologic evidence that ureidosuccinic acid and possibly ureido-fumaric acid (derived from 5-(carboxy-methylidine)-hydantoin) are precursors of the pyrimidine ring. Data on the distribution of orotic acid in nature are presented.Keywords
This publication has 5 references indexed in Scilit:
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