IN SEARCH OF NONRANDOM X-INACTIVATION - STUDIES OF FETAL MEMBRANES HETEROZYGOUS FOR GLUCOSE-6-PHOSPHATE-DEHYDROGENASE
- 1 January 1979
- journal article
- research article
- Vol. 31 (5), 581-585
Abstract
Extraembryonic membranes and fetal tissues were obtained from 55 specimens of 5-11 wk conceptual age. The glucose-6-phosphate dehydrogenase (G6PD) electrophoretic phenotype was determined and correlated with that of maternal blood. Fifteen specimens were heterozygous for G6PD A, and for 9 of these the maternal allele could be determined. In none of these specimens did the isozyme pattern of the membraneous chorion or chorionic villi differ significantly from that of fetal tissue. No evidence of non-random inactivation in extraembryonic membranes of human fetal specimens at this stage of development was seen.This publication has 8 references indexed in Scilit:
- Preferential X inactivation in human placenta membranes: Is the paternal X inactive in early embryonic development of female mammals?Human Genetics, 1978
- Preferential expression of the maternally derived X chromosome in the mouse yolk sacCell, 1977
- Glucose-6-phosphate dehydrogenase (G6PD) activity of human sperm.Journal of Medical Genetics, 1977
- COMPARISON OF GDA AND GDB ACTIVITIES IN NIGERIANS - STUDY OF VARIATION OF G6PD ACTIVITY1977
- Non-random inactivation of X chromosome in the rat yolk sacNature, 1976
- Preferential inactivation of the paternally derived X chromosome in the extraembryonic membranes of the mouseNature, 1975
- Evidence for the inactivation of an X chromosome early in the development of the human female.1975
- The Role of X-Chromosome Inactivation during SpermatogenesisProceedings of the National Academy of Sciences, 1972