Dynamics of amino acid residues in globular proteins

Abstract
The dynamic differential equation model developed and tested for bovine pancreatic trypsin inhibitor and tuna ferrocytochrome c was extended for 17 more protein crystals. Average displacements were computed for 20 amino acid residues observed in 19 proteins. Detailed information on the dynamic behavior of the individual proteins and individual residues was presented. The effect of atomic packing on the fluctuations of the amino acid residues in .alpha.-chymotrypsin is illustrated. A number of general points on the dynamic characteristics of globular protein molecules are presented.

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