The effect of salicylate on liver glycogen in the rat
- 1 June 1954
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 57 (2), 349-352
- https://doi.org/10.1042/bj0570349
Abstract
The effect of sodium salicylate on the liver glycogen and blood glucose of normal, adrenalectomized and adrenalectomized rats maintained on cortisone, are described. In the normal and adrenalectomized rats maintained on cortisone, a single dose of salicylate causes an initial impairment of the deposition of liver glycogen and a fall in blood glucose, but after 24 hours the levels of these substances are higher than in control animals. In adrenalectomized rats the initial effect of salicylate on liver glycogen and blood glucose is similar, but no recovery occurs after 24 hours. Some possible mechanisms to explain these effects are discussed.Keywords
This publication has 9 references indexed in Scilit:
- RELATIONSHIP OF THE ADRENAL GLANDS TO THE DIABETOGENIC EFFECT OF ETHYLENEDIAMINE IN THE PARTIALLY DEPANCREATIZED RATEndocrinology, 1953
- The effect of dinitro-o-cresol on the deposition of liver glycogen in the ratBiochemical Journal, 1953
- The effect of salicylate on the glycosuria and hyperglycaemia induced by cortisone in the normal ratBiochemical Journal, 1952
- Respiratory Effects of SalicylateBMJ, 1952
- The effect of salicylate on glycosuria, blood glucose and liver glycogen of the alloxan-diabetic ratBiochemical Journal, 1952
- THE ESTIMATION OF PLASMA-SALICYLATE LEVELS1950
- REVERSIBLE INHIBITION OF THE COUPLING BETWEEN PHOSPHORYLATION AND OXIDATIONJournal of Biological Chemistry, 1948
- THE RELATIONSHIP OF THE DIABETOGENIC EFFECT OF DIETHYLSTILBESTROL TO THE ADRENAL CORTEX IN THE RATAmerican Journal of Physiology-Legacy Content, 1943
- The effect of salicylate and cinchophen on enzymes and metabolic processesBiochemical Journal, 1942