MOUSE RBC ROSETTES IN CHRONIC LYMPHOCYTIC-LEUKEMIA - DIFFERENT EXPRESSION IN BLOOD AND TISSUES
- 1 January 1980
- journal article
- research article
- Vol. 39 (2), 411-415
Abstract
Mouse RBC (M) rosettes were investigated on lymphocytes from peripheral blood (PB) and various tissues in 20 patients with chronic lymphocytic leukemia and 1 with follicular lymphoma. In all cases studied, the percentage of M rosettes was significantly higher in PB (median 64%) than in bone marrow (median 15%) and lymph node (median 12%). These differences were statistically significant (P < 0.01). The possibility that these differences were related to technical factors was ruled out by a number of control procedures. The different expression of M rosette formation apparently reflects the property which determines whether a lymphocyte enters the peripheral blood or remains fixed in the tissues.This publication has 10 references indexed in Scilit:
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