HYPERADRENALCORTICISM IN A CASE OF ACROMEGALY WITH INSULIN-RESISTANT DIABETES*
- 1 April 1950
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 10 (4), 410-422
- https://doi.org/10.1210/jcem-10-4-410
Abstract
Detailed clinical, biochemical and hormonal observations on a 37-yr.-old male with acromegaly and insulin-resistant diabetes are presented. Maximum daily insulin dose was 650 units, and insulin requirement for over 7 mos. was about 300 units daily. X-ray treatment to the pituitary gave little immediate improvement. Stilbestrol therapy was also without clinical effect. Remission in the severity of the diabetes and return of the adrenal steroid excretion to normal occurred while the patient was receiving methyltestosterone.Keywords
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