Cortical cerebellar degeneration with ovarian carcinoma

Abstract

A case of subacute cortical cerebellar degeneration secondary to carcinoma of the ovary is presented. The chief clinical and pathologic features of the syndrome are described. The subacute development of bilateral cerebellar symptoms in a middle-aged person in the absence of a family history of cerebellar degeneration should lead to a painstaking search for an underlying carcinoma. Treatment is directed toward the underlying tumor and to the relief of symptoms. The theories of patho-genesis are discussed; none is completely satisfactory.