A comparative study of Lrrk2 function in primary neuronal cultures
- 1 December 2010
- journal article
- research article
- Published by Elsevier in Parkinsonism & Related Disorders
- Vol. 16 (10), 650-655
- https://doi.org/10.1016/j.parkreldis.2010.08.018
Abstract
No abstract availableKeywords
Funding Information
- Mayo Clinic
- NIH grants (NIA AG17216, NINDS NS40256)
- Michael J Fox Foundation
- and H. Lundbeck A/S
This publication has 27 references indexed in Scilit:
- Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinson's diseaseBiochemical Journal, 2009
- The Parkinson’s disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sitesBiochemical and Biophysical Research Communications, 2009
- TDP-43 Depletion Induces Neuronal Cell Damage through Dysregulation of Rho Family GTPasesJournal of Biological Chemistry, 2009
- Mutant LRRK2R1441G BAC transgenic mice recapitulate cardinal features of Parkinson's diseaseNature Neuroscience, 2009
- The Parkinson Disease Protein Leucine-Rich Repeat Kinase 2 Transduces Death Signals via Fas-Associated Protein with Death Domain and Caspase-8 in a Cellular Model of NeurodegenerationJournal of Neuroscience, 2009
- Identification of compounds that inhibit the kinase activity of leucine-rich repeat kinase 2Biochemical and Biophysical Research Communications, 2009
- Leucine-Rich Repeat Kinase 2 Mutations and Parkinson's Disease: Three QuestionsASN Neuro, 2009
- Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control studyThe Lancet Neurology, 2008
- The Roco protein family: a functional perspectiveThe FASEB Journal, 2008
- Roc, a Ras/GTPase domain in complex proteinsBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2003