Preparation of Specific Complement-Fixing Antigens from the Three Prototypes of Poliomyelitis Viruses.
- 1 January 1952
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 79 (1), 48-50
- https://doi.org/10.3181/00379727-79-19268
Abstract
Specific complement-fixing antigens were prepared from Lansing-, Brunhilde-, and Leon-infected tissues by sedimentation of the viruses in the high speed centrifuge and using the resuspended sediment as antigen. In the preparation of complement-fixing antisera in monkeys it was advantageous to mix the virus inoculum with an oily, depot-producing adjuvant.Keywords
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