RACK1 Competes with HSP90 for Binding to HIF-1α and Is Required for O2-Independent and HSP90 Inhibitor-Induced Degradation of HIF-1α
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Open Access
- 1 January 2007
- journal article
- research article
- Published by Elsevier in Molecular Cell
- Vol. 25 (2), 207-217
- https://doi.org/10.1016/j.molcel.2007.01.001
Abstract
No abstract availableKeywords
Funding Information
- National Heart, Lung, and Blood Institute (N01-HV28180)
This publication has 51 references indexed in Scilit:
- HIF-1 and tumour radiosensitivityBritish Journal of Cancer, 2006
- Hypoxia Preconditioning in the BrainDevelopmental Neuroscience, 2005
- OS-9 Interacts with Hypoxia-Inducible Factor 1α and Prolyl Hydroxylases to Promote Oxygen-Dependent Degradation of HIF-1αMolecular Cell, 2005
- Spatial and Temporal Regulation of RACK1 Function and N-methyl-D-aspartate Receptor Activity through WD40 Motif-mediated DimerizationPublished by Elsevier ,2004
- Aryl Hydrocarbon Nuclear Translocator (ARNT) Promotes Oxygen-independent Stabilization of Hypoxia-inducible Factor-1α by Modulating an Hsp90-dependent Regulatory PathwayJournal of Biological Chemistry, 2004
- Hsp90 Regulates a von Hippel Lindau-independent Hypoxia-inducible Factor-1α-degradative PathwayJournal of Biological Chemistry, 2002
- Identification of a surface on the β-propeller protein RACK1 that interacts with the cAMP-specific phosphodiesterase PDE4D5Cellular Signalling, 2001
- Mechanism of regulation of the hypoxia-inducible factor-1alpha by the von Hippel-Lindau tumor suppressor proteinThe EMBO Journal, 2000
- Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1αGenes & Development, 1998
- Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1Journal of Biological Chemistry, 1996